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危急重症医学部主任兼重症医学科主任,重症医学科主任医师,重症医学教研室主任,副教授,博士研究生导师。1992-1997,皖南医学院,本科;2002-2005,中山大学,硕士;2008-2011,暨南大学,博士。2005-2010,暨南大学附属第一医院,急诊科,主治医师;2010.12-至今,暨南大学附属第一医院,重症医学科,副主任医师/主任医师。长期参与和指导本科、硕士、博士和住院规培医师教学工作。全国高校教师教学创新大赛广东分赛三等奖(团队,2021年),一等奖(团队,2023)。2021年以来,主持社会医疗应急响应项目,探索和培训社会医疗应急志愿者,促进提高社会人员应对灾难的能力。
中国病理生理学会炎症发热专业委员会委员;广东省病理生理学会常务理事;广东省生物医学工程学会重症工程分会主任委员;广东省医疗安全协会急诊专委会副主任委员等。
主要研究方向为脓毒症、多器官功能障碍综合征和重症脑保护。截止2023年初,主持国家级、省市级科研项目6项,发表学术论文约20篇(部分为TOP期刊)。
2020年广东省第一批援鄂医疗队优秀临时党支部团体国家荣誉;2022年羊城好医生;2022年中国科协最美科技工作者提名。
2. Wen Lei, Zhiyao Ren, Jun Su, Xinglong Zheng ,Lijuan Gao, Yudai Xu, Jieping Deng, Chanchan Xiao, Shuai Shen, Yu Cheng, Tianshun Ma, Yu Liu, Pengcheng Wang, Oscar Junhong Luo, Guobing Chen and Zhigang Wang*. Immunological risk factors for sepsis-associated delirium and mortality in ICU patients. Frontiers in Immunology. 2022,20(13):940779.(IF20228.78)
3. Zhigang Wang#, Lu Gao, Shujing Ren, Guanghui Sun, Yanke Lin, Shuai Wang, Baojian Wu. E4BP4 Regulates Hepatic Solute Carrier Family 2 Member 9 and Uric Acid Disposition in Mice. Drug Metabolism and Disposition, 2022, 50(5): 591-599.(IF20223.920)
4. Fangjun Yu , Zhigang Wang# , Tianpeng Zhang , Xun Chen, Haiman Xu, Fei Wang, Lianxia Guo, Min Chen, Kaisheng Liu, Baojian Wu. Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding[J]. Nature communication , 2021, 12(1):5323. doi: 10.1038/s41467-021 -25674-5.(IF202114.919)
5. Min Chen, Yifei Xiao, Fugui Zhang, Jianhao Du, Li Zhang, Yifang Li, Danyi Lu 2, Zhigang Wang*, Baojian Wu. Tangeretin prevents cognitive deficit in delirium through activating RORα/γ-E4BP4 axis in mice. Biochem Pharmacol. 2022,205:115286.(IF2022 6.10)
6. Chanchan Xiao, Lipeng Mao, Zhigang Wang#, Lijuan Gao, Guodong Zhu, Jun Su,Xiongfei Chen,Jun Yuan,Yutian Hu, Zhinan Yin, Jun Xie,Weiqing Ji,Haitao Niu, Feng Gao,Oscar Junhong Luo, Lianbo Xiao, Pengcheng Wang, and Guobing Chen.SARS-CoV-2 variant B.1.1.7 caused HLA-A2+ CD8+ T cell epitope mutations for impaired cellular immune response. iScience.2022;25(3):103934.(IF20226.010)
7. Yi Wang, Zhigang Wang#, Zhengping Wu, Menglin Chen, Dong Dong, Pei Yu, Danyi Lu, Baojian Wu. Involvement of REV-ERBα dysregulation and ferroptosis in aristolochic acid I-induced renal injury. Biochem Pharmacol. 2021,193: 114807.DOI: 10.1016/j.bcp.2021.114807, PMID:34673015.(IF2021 5.858)
8. MengLin Chen, Min Chen, Danyi Lu, Yi Wang , Li Zhang, Zhigang Wang*, Baojian Wu.Period 2 Regulates CYP2B10 Expression and Activity in Mouse Liver. FRONT PHARMACOL. 2021,12: 764124. DOI: 10.3389/fphar.2021.764124.(IF2021 5.810)
9. Congling Qiu, Chanchan Xiao, Zhigang Wang#, Guodong Zhu, Lipeng Mao, Xiongfei Chen, Lijuan Gao, Jieping Deng, Jun Su, Huanxing Su, Evandro Fei Fang, Zhang-Jin Zhang, Jikai Zhang, Caojun Xie, Jun Yuan, Oscar Junhong Luo, Li An Huang, Pengcheng Wang, Guobing Chen. CD8(+) T-Cell Epitope Variations Suggest a Potential Antigen HLA-A2 Binding Deficiency for Spike Protein of SARS-CoV-2. FRONT IMMUNOL. 2021,12: 764949. DOI: 10.3389/fimmu.2021.764949 .(IF2021 7.500)
10. Lu D, Zhigang Wang*, Wu B. Pharmacokinetics-based Chronotherapy. Curr Drug Metab. 2022. 23(1):2-7.(IF2022 3.73)
11. 郑兴龙, 陈仁洲, 吴义,汪志刚*. 优化氧疗措施对COVID-19患者器官功能及预后的影响. 中国病理生理杂志, 2021,37(5):909-914.
曲栋,张群, 申丽,汪志刚*. 印度红树植物XYLOCAPUS的柠檬苦素. 天然药物和开发. 2021,33: 57-64.